Epidemiology and differential diagnosis of nasal polyps
نویسندگان
چکیده
BACKGROUND Chronic rhinosinusitis (CRS) is one of the most common chronic medical conditions, with a significant impact on patient quality of life. CRS is broadly classified into two groups: CRS with nasal polyposis (CRSwNP) and CRS without NP (CRSsNP). Clinically, the major subtypes of CRSwNP may be divided into eosinophilic chronic rhinosinusitis (e.g., allergic fungal rhinosinusitis and aspirin-exacerbated respiratory disease [AERD]) and nasal polyps associated with neutrophilic inflammation (e.g., cystic fibrosis [CF]). CF is characterized by mutation of the gene encoding the CF transmembrane conductance regulator. Functional endoscopic sinus surgery is usually required for most NP patients with increased frequency in patients with AERD. This study provides a review of the epidemiology and major classification of CRSwNP. METHODS A review was performed of the literature regarding different subtypes of CRSwNP. RESULTS Many definitions of CRSwNP exist and estimates of prevalence vary. CONCLUSION CRSwNP is a clinical syndrome with a heterogeneous inflammatory profile. Of the subtypes associated with eosinophilic inflammation, AERD remains the most recalcitrant to medical and surgical therapeutic interventions.
منابع مشابه
The Epidemiological and Clinical Aspects of Nasal Polyps that Require Surgery
Introduction: The objective of this retrospective cross-sectional study was to obtain epidemiological data from the charts of 297 patients with nasal polyposis who were operated on in a referral hospital in Mashhad and to determine the frequency of the presenting symptoms of nasal polyps. Materials and Methods: The variables recorded included age, gender, the presence of asthma or allergic...
متن کاملParaganglioma of the skull base presenting as nasal polyps.
The authors report a case of paraganglioma of the skull base presenting as nasal polyps. A 29-year-old patient presented with epistaxis and was found to have nasal polyps. The patient underwent a nasal polypectomy. After pathology showed an unusual appearance, the mass was subsequently excised endoscopically using radiofrequency coblation, and it was found to be originating from the skull base....
متن کاملQualitaty of Olfaction in Patients with Nasal and Sinuses Polyposis before and after Endo-scopic Sinus Surgery in, Vali e Asr Hospital in 2017
Background: Olfaction plays an important role in human life and promotes quality of life through understanding various odors. Nasal polyps are among the common causes of olfactory impairment. There are many different treatment options for polyps most notably the diagnosis and elimination of underlying causes. Some polyps do not respond to medication therapy or they relapse, and therefore requir...
متن کاملInflammatory Septal Nasal Polyp
Introduction: Nasal polyps are benign prolapsed mucosal lesions which commonly arise from the paranasal sinuses and lateral walls of the nose especially the contact areas of osteomeatal complex. Though nasal polyps arising from the nasal septum have been reported, those arising from its anterior part are extremely rare and present a diagnostic dilemma. Aetiology is multifactorial and is mainl...
متن کاملSphenochoanal polyps and the optic nerve
Isolated sphenoid pathology is uncommon. Nasal polyps that originate from the anterior wall of the sphenoid sinus and reach the nasopharynx are called sphenochoanal polyps. The atypical location of sphenochoanal polyps leads to misdiagnosis, and surgery risks injuring the surrounding structures, such as the optic nerve, carotid artery, and brain. For the differential diagnosis of sphenochoanal ...
متن کامل